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Isolation of swine-like influenza A(H1N1) viruses from man in Switzerland and The Netherlands

Identifieur interne : 002247 ( Main/Exploration ); précédent : 002246; suivant : 002248

Isolation of swine-like influenza A(H1N1) viruses from man in Switzerland and The Netherlands

Auteurs : J. C. De Jong [Pays-Bas] ; M. F. Paccaud [Suisse] ; F. M. De Ronde-Verloop [Pays-Bas] ; N. H. Huffels [Pays-Bas] ; C. Verwei [Pays-Bas] ; T. F. Weijers [Pays-Bas] ; P. J. Bangma [Pays-Bas] ; E. Van Kregten [Pays-Bas] ; J. A. M. Kerckhaert [Pays-Bas] ; F. Wicki ; W. Wunderli [Suisse]

Source :

RBID : ISTEX:481EFB8D2E03D941D06B047F71CEA5D4363012EF

Descripteurs français

English descriptors

Abstract

Summary: Swine influenza A (H1N1) viruses were isolated from two people in Switzerland and one in the Netherlands in early 1986. In haemagglutination-inhibition and neuraminidase-inhibition assays, the three viruses were closely related to one another and to the A/New Jersey/8/76 strain. The Swiss patients showed only mild symptoms, whereas the Dutch patient suffered from severe pneumonia. Two of the patients had been in close contact with diseased pigs. No such contact could be established for the third patient. None of the three individuals was known to suffer from immunodeficiency. No man-to-man transmission of the virus has been detected.
Résumé: Trois souches de virus de la grippe porcine «classiqueå A(H1N1) ont été isolées chez l'homme (deux cas en Suisse, un cas aux Pays-Bas), au début de l'année 1986. Ces souches sont, sur le plan antigénique, étroitement apparentées entre elles et proches de la souche Influenza A/New Jersey/8/76(SwH1N1). Les sujets suisses n'ont présenté qu'une affection bénigne alors que le malade hollandais a souffert d'une pneumonie grave. Dans deux de ces trois cas, il y avait eu un contact étroit avec des porcs atteints de grippe porcine. Aucun des trois sujects ne présentait de déficience immunologique. On n'a pas pu mettre en évidence de transmission interhumaine du virus.

Url:
DOI: 10.1016/S0769-2617(88)80078-9


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="fr">Résumé: Trois souches de virus de la grippe porcine «classiqueå A(H1N1) ont été isolées chez l'homme (deux cas en Suisse, un cas aux Pays-Bas), au début de l'année 1986. Ces souches sont, sur le plan antigénique, étroitement apparentées entre elles et proches de la souche Influenza A/New Jersey/8/76(SwH1N1). Les sujets suisses n'ont présenté qu'une affection bénigne alors que le malade hollandais a souffert d'une pneumonie grave. Dans deux de ces trois cas, il y avait eu un contact étroit avec des porcs atteints de grippe porcine. Aucun des trois sujects ne présentait de déficience immunologique. On n'a pas pu mettre en évidence de transmission interhumaine du virus.</div>
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